Affective Neuroscience and Pain Lab

Selected Publications:

• Atlas LY, Dildine TC, Palacios-Barrios EE, Yu Q, Reynolds RC, Banker LA, Grant SS, Pine DS. Instructions and experiential learning have similar impacts on pain and pain-related brain responses but produce dissociations in value-based reversal learning. eLife. 2022;11:e73353.
• Amir C, Rose-McCandlish M, Weger R, Dildine TC, Mischkowski D, Necka EA, Lee IS, Wager TD, Pine DS, Atlas LY. Test-retest reliability of an adaptive thermal pain calibration procedure in healthy volunteers. Journal of Pain. 2022;23(9):1543-1555.
• Motzkin JC, Hiser J, Carroll I, Wolf R, Baskaya MK, Koenigs M, Atlas LY. Human ventromedial prefrontal cortex lesions enhance the effect of expectations on pain perception. Cortex. 2023;166:188-206.
• Necka EA, Amir C, Dildine TC, Atlas LY. Expectations about pain and analgesic treatment are shaped by medical providers’ facial appearances: evidence from five online clinical simulation experiments. Social Science & Medicine. 2021;281:114091. 
• Atlas LY. How instructions, learning, and expectations shape pain and neurobiological responses. Annual Review of Neuroscience. 2023;46:167-189.

Other Publications

• Dildine TC, Amir CM, Parsons J, and Atlas LY. How pain-related facial expressions are evaluated in relation to gender, race, and emotion. Affective Science. 2023;4(2):350-369.
• Weger R, Lossio-Ventura J-A, Rose-McCandlish M, Shaw J, Sinclair S, Pereira F, Chung J, Atlas LY. Trends in language use during the COVID-19 pandemic and relationship between language use and mental health: text analysis based on free responses from a longitudinal study. JMIR Mental Health. 2023;10:e40899.
• Atlas LY. How instructions, learning, and expectations shape pain and neurobiological responses. Annual Review of Neuroscience. 2023;46:167-189.
• Atlas LY, Dildine TC, Palacios-Barrios EE, Yu Q, Reynolds RC, Banker LA, Grant SS, Pine DS. Instructions and experiential learning have similar impacts on pain and pain-related brain responses but produce dissociations in value-based reversal learning. eLife. 2022;11:e73353.
• Atlas LY, Sandman CF, Phelps EA. Rating expectations can slow aversive learning. Psychophysiology. 2021 Nov 27 [epub ahead of print].
• Abend R, Ruiz SG, Bajaj MA, Harrewijn A, Linke JO, Atlas LY, Pine DS. Threat imminence reveals distinct links among anxiety, anticipatory physiological response, and cortical-subcortical intrinsic functional connectivity. Neurobiology of Stress. 2022;16:100428. 
• Han X, Ashar YK, Kragel P, Petre B, Schelkun V, Atlas LY, Chang LJ, Jepma M, Koban L, Losin EAR, Roy M, Woo C-W, Wager TD. Effect size and test-retest reliability of the fMRI-based neurologic pain signature. Neuroimage. 2021;247:118844.
• Atlas LY. A social affective neuroscience lens on placebo analgesia. Trends in Cognitive Sciences. 2020;25(11):992-1005. 
• Lebedev AV, Acar K, Garzón B, Almeida R, Råback J, Åberg A, Martinsson S, Olsson A, Martinsson S, Olsson A, Louzolo A, Pärnamets P, Lövden M, Atlas LY, Ingvar M, Petrovic P. Psychedelic drug use and schizotypy in young adults. Scientific Reports, 2021;11(1):15058.
• Necka EA, Amir C, Dildine TC, Atlas LY. Expectations about pain and analgesic treatment are shaped by medical providers’ facial appearances: evidence from five online clinical simulation experiments. Social Science & Medicine. 2021;281:114091. 
• Mischkowski D, Stavish CM, Palacios-Barrios EE, Banker LA, Dildine TC, Atlas LY. Dispositional mindfulness and acute heat pain: comparing stimulus-evoked pain with summary pain assessment. Psychosomatic Medicine. 2021;83(6):539-548.
• Abend R, Bajaj MA, Harrewijn A, Matsumoto C, Michalska KJ, Necka E, Palacios-Barrios EE, Liebenluft E, Atlas LY, Pine DS. Threat-anticipatory psychophysiological response is enhanced in pediatric anxiety and correlates with prefrontal cortex structure. Journal of Psychiatry and Neuroscience. 2021;46(2):E212-E221. 
• Zunhammer M, Spisák T, Wager TD, Bingel U, Placebo Imaging Consortium. Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data. Nature communications. 2021;12(1):1391. (Member of Placebo Imaging Consortium).
• Evers AWM, Colloca L, Blease C, Gaab J, Jensen KB, Atlas LY, et al. “Consensus on placebo and nocebo effects connects science and practice: reply to “Questioning the consensus on placebo and nocebo effects”. Psychotherapy and Psychosomatics. 2021;90(3):213-214. (Pain Research Forum Editors’ Pick).
• Dildine TC, Necka EA, Atlas LY. Confidence in subjective pain is predicted by reaction time during decision making. Scientific Reports. 2020;10(1):21373. 
• Gruber J, Mendle J, Lindquist KA, Schmader T, Clark LA, Bliss-Moreau E, Akintola M, Atlas LY, et al. The future of women in psychological science. Perspectives on Psychological Science. 
• Leknes S, Atlas LY. Flawed methodology undermines conclusions about opioid-induced pleasure: implications for psychopharmacology. British Journal of Anesthesia. 2020;124(3):e29-e33.
• Geuter S, Roy M, Reynolds Losin EA, Atlas LY, Schmidt L, Krishnan A, Koban L, Wager TD, Lindquist MA. Multiple brain networks mediating stimulus-pain relationships in humans. Cerebral Cortex. 2020;30(7):4204-4219.
• Rahnev D, Desender K, Lee ALF, Adler WT, Aguilar-lleyda D, Akdogan B, Arbuzova P, Atlas LY, et al. The confidence database. Nature Human Behaviour. 2020;4:317-325.
• Zheng W, Woo CW, Yao Z, Goldstein P, Atlas LY, Roy M, Schmidt L, Krishnan A, Jepma M, Hu B, Wager TD. Pain-evoked reorganization in functional brain networks. Cerebral Cortex. 2020;30(5):2804-2822.
• Lee IS, Necka EA, Atlas LY. Distinguishing pain from nociception, salience, and arousal: how autonomic nervous system activity can improve neuroimaging tests of specificity. Neuroimage. 2020;204:116254.
• Atlas LY, Palacios-Barrios E, Dildine TC, et al. (In press). Anxious individuals update expectations and reported pain in response to instructions during aversive reversal learning, but maintain sustained arousal for initial threats. Journal of Abnormal Psychology.
• Necka EA, Lee IS, Kucyi A, Cheng JC, Yu Q, Atlas LY. Applications of dynamic functional connectivity to pain and its modulation. Pain Reports. 2019;4(4):e752.
• Dildine TC, Atlas LY. The need for diversity in research on facial expressions of pain. Pain. 2019;160(8):1901-1902.
• Mischkowski D, Atlas LY. Reply to Zaman et al. Pain. 2019;160(6):1485-1486.
• Mischkowski D, Palacios-Barrios E, Banker LA, Dildine TC, Atlas LY. Pain or nociception? Subjective experience mediates the effects of heat on autonomic responses–corrected and republished. Pain. 2019;160(6):1469-1481.
• Atlas LY. How instructions shape aversive learning: higher order knowledge, reversal learning, and the role of the amygdala. Current Opinions in Behavioral Sciences. 2019;26:121-129. 
• Atlas LY, Doll BB, Li J, Daw ND, Phelps EA. How instructed knowledge shapes adaptive learning. PsyArXiv. 2018;doi:10.31234/osf.io/f4sh9.
• Atlas LY, al’Absi M. The neuroscience of pain: biobehavioral, developmental, and psychosocial mechanisms relevant to intervention targets. Psychosomatic Medicine. 2018;80(9):788-790.
• Case LK, Laubacher CM, Richards EA, Grossman M, Atlas LY, Parker S, Bushnell MC. Is placebo analgesia for heat pain a sensory effect? An exploratory study on minimizing the influence of response bias. Neurobiology of Pain. 2019;5:100023.
• Zunhammer M, Bingel U, Wager TD, Atlas LY, et al. Placebo effects on the neurologic pain signature: a meta-analysis of individual participant functional magnetic resonance imaging data. JAMA Neurology. 2018;75(11):1321-1330.
• Michalska KJ, Feldman JS, Abend R, Gold AL, Dildine TC, Palacios-Barrios EE, Leibenluft E, Towbin KE, Pine DS, Atlas LY. Anticipatory effects on perceived pain: associations with development and anxiety. Psychosomatic Medicine. 2018;80(9):853-860.
• Evers AWM, Colloca L, Blease C, Klinger R, Annoni M, Atlas LY, et al. Implications of placebo and nocebo effects for clinical practice: expert consensus. Psychotherapy and Psychosomatics. 2018;87(4):204-210.
• Moayedi M, Salomons TV, Atlas LY. Pain neuroimaging in humans: a primer for beginners and non-imagers. Journal of Pain. 2018;19(9):961.e1-961.e21.
• Atlas LY, Phelps EA. Prepared stimuli enhance aversive learning without weakening the impact of verbal instructions. Learning & Memory. 2018;25(2):100-104.
• Necka EA, Atlas LY. The role of social and interpersonal factors in placebo analgesia. In: Colloca L, ed. Neurobiology of the Placebo Effect, Part I. International Review of Neurobiology. Vol. 138. Cambridge, MA: Academic Press; 2018:161-179.
• Atlas LY. How are emotions regulated by context and cognition? The role of context and cognition in the placebo effect. In: Fox AS, Lapate RC, Shackman AJ, et al, eds. The Nature of Emotion. Fundamental Questions. New York, NY: Oxford University Press; 2018:158-161.
• Woo C-W, Schmidt L, Krishnan A, Jepma M, Roy M, Lindquist M, Atlas LY, Wager TD. Quantifying cerebral contributions to pain beyond nociception. Nature Communications. 2017;8:14211.
• Atlas LY, Doll BB, Li J, Daw NE, Phelps EA. Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala. eLife. 2016;5:e15192.
• Wager TD, Atlas LY. The neuroscience of placebo effects: connecting context, learning, and health. Nature Reviews Neuroscience. 2015;16:403-418.
• Robinson LF*, Atlas LY*, Wager TD. Dynamic functional connectivity using State-based Dynamic Community Structure: method and application to opioid analgesia. Neuroimage. 2015;108:274-291. *Equal authorship contributions.
• Atlas LY, Wager TD. A meta-analysis of brain mechanisms of placebo analgesia: consistent findings and unanswered questions. In: Benedetti F, Enck P, Frisaldi E, Schedlowski M, eds. Handbook of Experimental Pharmacology—Placebo. 2014;225:37-69.
• Atlas LY, Lindquist MA, Bolger N, et al. Brain mediators of the effects of noxious heat on pain. Pain. 2014;155(8):1632-1648.
• Atlas LY, Wielgosz J, Whittington RA, et al. Specifying the non-specific factors underlying opioid analgesia: expectancy, attention, and affect. Psychopharmacology. 2014;231(5):813-823.

See the full list of publications for Lauren Y. Atlas, Ph.D. on PubMed.