Because of a lapse in Government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding Government operating status and resumption of normal operations can be found at OPM.gov.

A Closer Look at 7-HMG, MG, and Some Safety Issues

7 of 12

Runtime: 6:04

Dr. McCurdy explains more about the binding and function of 7-HMG. Although not present in the fresh leaves, 7-HMG has been found at levels from nonexistent to very high in scientists’ analyses of kratom products. He discusses the “buyer beware” environment around kratom products. A study is presented on what happened when MG and 7-HMG were substituted for morphine in studies of animals. Other questions include whether these two constituents of kratom are potentially abusable and addictive, and whether mode of administration makes a difference. Metabolism is introduced.