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National Center for Complementary and Integrative Health

NCCIH Clinical Trials Funding Opportunities

The National Center for Complementary and Integrative Health (NCCIH) no longer accepts most clinical trial applications through the Parent R01 (NOT-AT-20-001). Instead, NCCIH has published a series of clinical trial-specific Notices of Funding Opportunities (NOFOs) for investigators to use instead of the Parent R01. These NOFOs focus on 1) mind and body intervention studies and 2) natural product studies, targeting support of all phases of clinical intervention development.

NCCIH Research Framework - Basic (How does it work?), Mechanistic and Translational (Can the mechanistic effect be measured reliably; could it translate to humans?), Intervention Refinement and Optimization (Can modification enhance impact or adherence?), Efficacy (Does it work when compared to appropriate comparison condition?), Effectiveness and Pragmatic Studies (Is it still effective when implemented in "real world" conditions?), Dissemination and Implementation Science (How do we facilitate uptake in various settings?)